Articles with "dinactin" as a keyword



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Streptomyces puniceus strain AS13., Production, characterization and evaluation of bioactive metabolites: A new face of dinactin as an antitumor antibiotic.

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Published in 2018 at "Microbiological research"

DOI: 10.1016/j.micres.2017.12.004

Abstract: A highly active actinobacterial strain isolated from untapped areas of Northwestern Himalayas and characterised as Streptomyces puniceus strain AS13 by 16S rRNA gene sequencing was selected for production of bioactive metabolites. The bioassay-guided fractionation of… read more here.

Keywords: strain as13; bioactive metabolites; streptomyces puniceus; puniceus strain ... See more keywords
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Dinactin: A New Antitumor Antibiotic with Cell Cycle Progression and Cancer Stemness Inhibiting Activities in Lung Cancer

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics11121845

Abstract: Lung cancer, especially non-small cell lung cancer (NSCLC), is one of the most complex diseases, despite the existence of effective treatments such as chemotherapy and immunotherapy. Since cancer stem cells (CSCs) are responsible for chemo-… read more here.

Keywords: lung cancer; cell; cancer stemness; cancer ... See more keywords