Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aba3688
Abstract: Metabolic analysis of ADA2-deficient cells shows that extracellular purine nucleosides trigger cellular innate immunity. Mechanisms linking immune sensing of DNA danger signals in the extracellular environment to innate pathways in the cytosol are poorly understood.… read more here.
Keywords: purine nucleosides; ifn response; dino; extracellular purine ... See more keywords
Long non-coding RNA DINO promotes cisplatin sensitivity in lung adenocarcinoma via the p53-Bax axis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Thoracic Disease"
DOI: 10.21037/jtd-23-465
Abstract: Background The damage-induced non-coding (DINO) RNA is a newly identified long non-coding RNA (lncRNA) found in human cells with DNA damage. The treatment of tumors with cisplatin can induce DNA damage; however, whether the lncRNA… read more here.
Keywords: dino; lung; p53 bax; p53 ... See more keywords
Tuning Gel State Properties of Supramolecular Gels by Functional Group Modification
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24193472
Abstract: The factors affecting the self-assembly process in low molecular weight gelators (LMWGs) were investigated by tuning the gelation properties of a well-known gelator N-(4-pyridyl)isonicotinamide (4PINA). The N―H∙∙∙N interactions responsible for gel formation in 4PINA were… read more here.
Keywords: tuning gel; gelation; dino; gel state ... See more keywords