Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Toxicology"
DOI: 10.1007/s00204-018-2378-6
Abstract: Diisononyl phthalate (DiNP) is a plasticizer used to improve plastic performance in a large variety of items which has been reported as an endocrine-disrupting chemical (EDC) in several organisms. The endocannabinoid system (ECS) is a cellular signaling… read more here.
Keywords: gilthead sea; dinp; sea bream; season ... See more keywords
Dietary diisononylphthalate contamination induces hepatic stress: a multidisciplinary investigation in gilthead seabream (Sparus aurata) liver
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02494-7
Abstract: In this study, adult gilthead seabream (Sparus aurata) were exposed for 21 days to Di-iso-nonylphthalte (DiNP at 15 and 1500 μg kg−1 bw day−1) via the diet. This plastic additive has been recently introduced to replace the di-(2-ethylhexyl)phthalate, the toxicity… read more here.
Keywords: seabream sparus; dinp; gilthead seabream; stress ... See more keywords
Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model
Sign Up to like & getrecommendations! Published in 2024 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-024-03454-4
Abstract: Diisononyl phthalate (DiNP) has been associated with the development of allergies, asthma, and allergic airway inflammation. Through a complex interplay of signals and feedback mechanisms, the lungs communicate with the heart to ensure maintenance of… read more here.
Keywords: oxidative stress; group; dinp induced; dinp ... See more keywords
Exposure to phthalates DEHP and DINP May lead to oxidative damage and lipidomic disruptions in mouse kidney.
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DOI: 10.1016/j.chemosphere.2021.129740
Abstract: Di(2-ethylhexyl) phthalate (DEHP) has been well acknowledged for its endocrine disruption and associated metabolic diseases, leading to the search for safer industrial alternatives including di-isononyl phthalate (DINP). However, safety data for the latter chemical has… read more here.
Keywords: dinp; oxidative damage; exposure; dehp dinp ... See more keywords
Exposure to diisononyl phthalate promotes atopic march by activating of NF-κB and p38 MAPK.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.114981
Abstract: What factors and underlying mechanisms influence the occurrence of the atopic march remain unclear. Recent studies suggest that exposure to diisononyl phthalate (DINP) might be associated with the occurrence of atopic dermatitis (AD) and asthma.… read more here.
Keywords: march; p38 mapk; dinp; exposure ... See more keywords
Investigation of protective effects of rutin\cyclodextrin inclusion complex against testicular damage caused by diisononyl phthalate in rats
Sign Up to like & getrecommendations! Published in 2025 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2025.87549.18910
Abstract: Objective(s): The aim of this study was to investigate the protective effects of Rutin\cyclodextrin (RUT\CD) complex in rats exposed to diisononyl phthalate (DINP). Materials and Methods: In the study, 35 male Sprague Dawley rats were… read more here.
Keywords: rut; protective effects; effects rutin; rutin cyclodextrin ... See more keywords
Probiotics as Potential Tool to Mitigate Nucleotide Metabolism Alterations Induced by DiNP Dietary Exposure in Danio rerio
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252011151
Abstract: Diisononyl phthalate, classified as endocrine disruptor, has been investigate to trigger lipid biosynthesis in both mammalian and teleostean animal models. Despite this, little is known about the effects of DiNP exposure at tolerable daily intake… read more here.
Keywords: tool mitigate; metabolism alterations; metabolism; nucleotide metabolism ... See more keywords
Isolation of DiNP-Degrading Microbes from the Mouse Colon and the Influence DiNP Exposure Has on the Microbiota, Intestinal Integrity, and Immune Status of the Colon
Sign Up to like & getrecommendations! Published in 2022 at "Toxics"
DOI: 10.3390/toxics10020075
Abstract: Di-isononyl phthalate (DiNP) is a plasticizer used to impart flexibility or stability in a variety of products including polyvinyl chloride, cable coatings, artificial leather, and footwear. Previous studies have examined the impact of DiNP on… read more here.
Keywords: dinp; dinp degrading; dinp exposure; immune ... See more keywords