Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model
Sign Up to like & getrecommendations! Published in 2024 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-024-03454-4
Abstract: Diisononyl phthalate (DiNP) has been associated with the development of allergies, asthma, and allergic airway inflammation. Through a complex interplay of signals and feedback mechanisms, the lungs communicate with the heart to ensure maintenance of… read more here.
Keywords: oxidative stress; group; dinp induced; dinp ... See more keywords
Inhibitions of HMGB1 and TLR4 alleviate DINP-induced asthma in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology research"
DOI: 10.1039/c9tx00048h
Abstract: We studied the effects of high mobility group box chromosomal protein 1 (HMGB1) and toll-like receptor (TLR4) in diisonoyl phthalate (DINP)-induced asthma. Mice with DINP-induced asthma were treated with a TLR4-signaling inhibitor or anti-HMGB1 antibody,… read more here.
Keywords: induced asthma; dinp induced; hmgb1; asthma mice ... See more keywords