Biotransformation of Dec-604 and potential effect on thyroid deiodinase activity in highly flame retardant-exposed gulls.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental research"
DOI: 10.2139/ssrn.4126069
Abstract: Several halogenated flame retardants (HFRs) have been identified as thyroid disruptors in birds including the polybrominated diphenyl ether (PBDE) mixtures, which have been replaced with other HFRs such as Dechlorane-604 (Dec-604). Dec-604 Component B (Dec-604… read more here.
Keywords: effect; dio1; deiodinase; activity ... See more keywords
Insights into the Mechanism of Human Deiodinase 1
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DOI: 10.3390/ijms23105361
Abstract: The three isoenzymes of iodothyronine deiodinases (DIO1-3) are membrane-anchored homo-dimeric selenoproteins which share the thioredoxin-fold structure. Several questions regarding their catalytic mechanisms still remain open. Here, we addressed the roles of several cysteines which are… read more here.
Keywords: human deiodinase; mechanism human; insights mechanism; dio1 ... See more keywords