Effect of antithyroid drugs on the occurrence of antibodies against type 2 deiodinase (DIO2), which are involved in hyperthyroid Graves’ disease influencing the therapeutic efficacy
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DOI: 10.1007/s10238-018-00542-7
Abstract: Graves’ disease is an organ-specific autoimmune disease with hyperthyroidism, diffuse goiter and autoantibodies against TSH receptor, thyroid peroxidase (TPO) and/or thyroglobulin (Tg). Graves’ hyperthyroidism is characterized by T3 dominance due to the conversion of T4… read more here.
Keywords: peptide antibodies; type deiodinase; antithyroid drugs; dio2 ... See more keywords
Age Worsens the Cognitive Phenotype in Mice Carrying the Thr92Ala-DIO2 Polymorphism
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DOI: 10.3390/metabo12070629
Abstract: The Thr92Ala-Dio2 polymorphism has been associated with reduced cognition in 2-month-old male mice and increased risk for cognitive impairment and Alzheimer’s disease in African Americans. This has been attributed to reduced thyroid hormone (TH) signaling… read more here.
Keywords: dio2 polymorphism; phenotype; thr92ala dio2; dio2 ... See more keywords