Ruthenium-catalyzed synthesis of N-substituted lactams by acceptorless dehydrogenative coupling of diols with primary amines.
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DOI: 10.1039/c9cc06339k
Abstract: Herein, we report the first example of synthesis of N-substituted lactams via an acceptorless dehydrogenative coupling of diols with primary amines in one step, which was enabled by combining Ru3(CO)12 with a hybrid N-heterocyclic carbene-phosphine-phosphine… read more here.
Keywords: substituted lactams; synthesis substituted; diols primary; coupling diols ... See more keywords