Thieno[3,4-c]Pyrrole-4,6-Dione-Based Polymer Acceptors for High Open-Circuit Voltage All-Polymer Solar Cells
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Energy Materials"
DOI: 10.1002/aenm.201602574
Abstract: S.L. and X.S. contributed equally to this work. The authors acknowledge financial support under Baseline Research Funding from King Abdullah University of Science and Technology (KAUST) and from ONR-Global (Award No. N62909-15-1-2003 to J.L.B.). The… read more here.
Keywords: thieno pyrrole; based polymer; polymer; polymer acceptors ... See more keywords
Quinazolin-2,4-dione-Based Hydroxamic Acids as Selective Histone Deacetylase-6 Inhibitors for Treatment of Non-Small Cell Lung Cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b01590
Abstract: We designed and synthesized quinazolin-2,4-dione-based hydroxamic acids to serve as selective competitive inhibitors of histone deacetylase-6 (HDAC6). The most potent and selective compound, 3d (IC50, 4 nM, HDAC6; IC50 > 10 μM, HDAC1), substantially increased… read more here.
Keywords: based hydroxamic; quinazolin dione; lung cancer; cancer ... See more keywords
Molecular Modeling and Synthesis of Indoline-2,3-dione-Based Benzene Sulfonamide Derivatives and Their Inhibitory Activity against α-Glucosidase and α-Amylase Enzymes
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DOI: 10.1021/acsomega.3c01130
Abstract: Diabetes is also known as a critical and noisy disease. Hyperglycemia, that is, increased blood glucose level is a common effect of uncontrolled diabetes, and over a period of time can cause serious effects on… read more here.
Keywords: glucosidase amylase; amylase; dione based; based benzene ... See more keywords
Janus Dione-Based Conjugated Covalent Organic Frameworks with High Conductivity as Superior Cathode Materials.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c10509
Abstract: The development of conductive covalent organic frameworks (COFs) with high stability is desirable for the practical applications in optoelectronics and energy storage. Herein, we developed a new kind of Janus dione-based COF, which is fully… read more here.
Keywords: organic frameworks; conductivity; covalent organic; dione based ... See more keywords
Discovery of New 3,3-Diethylazetidine-2,4-dione Based Thiazoles as Nanomolar Human Neutrophil Elastase Inhibitors with Broad-Spectrum Antiproliferative Activity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147566
Abstract: A series of 3,3-diethylazetidine-2,4-dione based thiazoles 3a–3j were designed and synthesized as new human neutrophil elastase (HNE) inhibitors in nanomolar range. The representative compounds 3c, 3e, and 3h exhibit high HNE inhibitory activity with IC50… read more here.
Keywords: diethylazetidine dione; neutrophil elastase; human neutrophil; based thiazoles ... See more keywords
Synthesis and Structure–Activity Relationship Studies of Benzimidazole-4,7-dione-Based P2X3 Receptor Antagonists as Novel Anti-Nociceptive Agents
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27041337
Abstract: P2X3 receptors (P2X3R) are ATP-gated ion channels predominantly expressed in C- and Aδ-fiber primary afferent neurons and have been introduced as a novel therapeutic target for neurological disorders, including neuropathic pain and chronic cough. Because… read more here.
Keywords: structure activity; structure; benzimidazole dione; anti nociceptive ... See more keywords