Dioscorea nipponica extracts enhance recovery from skeletal muscle atrophy by suppressing NF-κB expression
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.104109
Abstract: Abstract Saponin derived from natural extracts can alleviate muscle atrophy. Dioscorea nipponica Makino (DNM) is commonly used in herbal medicine and contains various steroidal saponins, although its efficacy and mechanisms of action for treating muscle… read more here.
Keywords: dioscorea nipponica; muscle; dnm; expression ... See more keywords
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves’ Disease—On Network Pharmacology and Experimental Evaluation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.806829
Abstract: Dioscorea nipponica rhizoma (DNR) is commonly used for the cure of hyperthyroidism resulting from Graves’ disease (GD) or thyroid nodules. However, its therapeutic mechanism remains unclear. This study aimed to utilize network pharmacology integrated molecular… read more here.
Keywords: graves disease; network pharmacology; nipponica rhizoma; pharmacology ... See more keywords
Weighted Gene Co-expression Network Analysis of the Dioscin Rich Medicinal Plant Dioscorea nipponica
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2017.00789
Abstract: Dioscorea contains critically important species which can be used as staple foods or sources of bioactive substances, including Dioscorea nipponica, which has been used to develop highly successful drugs to treat cardiovascular disease. Its major… read more here.
Keywords: dioscorea nipponica; plant; dioscorea; gene expression ... See more keywords
Dioscorea nipponica Makino Rhizome Extract and Its Active Compound Dioscin Protect against Neuroinflammation and Scopolamine-Induced Memory Deficits
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179923
Abstract: Activation of microglial cells by intrinsic or extrinsic insult causes neuroinflammation, a common phenomenon in neurodegenerative diseases. Prevention of neuroinflammation may ameliorate many neurodegenerative disease progressions. Dioscorea nipponica Makino (DN) extract can alleviate muscular atrophy… read more here.
Keywords: nipponica makino; compound dioscin; dioscorea nipponica; active compound ... See more keywords