Breathing air as oxidant: Optimization of 2-chloro-2-oxo-1,3,2-dioxaphospholane synthesis as a precursor for phosphoryl choline derivatives and cyclic phosphate monomers
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DOI: 10.1016/j.tet.2017.05.037
Abstract: Abstract Phosphoryl choline derivatives are important compounds for drug development. Also other phosphoesters have received increased demand in recent years. Many of such compounds rely 2-chloro-2-oxo-1,3,2-dioxaphospholane (COP) as an intermediate. COP is available in a… read more here.
Keywords: dioxaphospholane; choline derivatives; chloro oxo; phosphoryl choline ... See more keywords