2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces peripheral blood abnormalities and plasma cell neoplasms resembling multiple myeloma in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.10.009
Abstract: Although epidemiologic studies have suggested a possible association between occupational exposures to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the risk of development of multiple myeloma, definitive evidence in support of this association is lacking. In the present study,… read more here.
Keywords: myeloma; tcdd; dioxin tcdd; multiple myeloma ... See more keywords
Transgenerational impairment of ovarian induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) associated with Igf2 and H19 in adult female rat.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology"
DOI: 10.1016/j.tox.2019.152311
Abstract: 2,3,7,8-Tetrachlorobenze-p-dioxin (TCDD), one of representive Endocrine Disrupting Chemicals (EDCs), has potential adverse effects on human health. Direct exposure to TCDD has been implicated in ovarian follicles development and functions deficits in adulthood. However, it is… read more here.
Keywords: tcdd; igf2 h19; dioxin tcdd; exposure ... See more keywords
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-elicited effects on bile acid homeostasis: Alterations in biosynthesis, enterohepatic circulation, and microbial metabolism
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DOI: 10.1038/s41598-017-05656-8
Abstract: Abstract2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant which elicits hepatotoxicity through activation of the aryl hydrocarbon receptor (AhR). Male C57BL/6 mice orally gavaged with TCDD (0.01–30 µg/kg) every 4 days for 28 days exhibited bile duct… read more here.
Keywords: bile; metabolism; dioxin tcdd; tetrachlorodibenzo dioxin ... See more keywords