Three-component Synthesis of 4-Arylidene-3-alkylisoxazol-5(4H)-ones in the Presence of Potassium 2,5-dioxoimidazolidin-1-ide
Sign Up to like & getrecommendations! Published in 2021 at "Current Organic Chemistry"
DOI: 10.2174/1385272825666210212120517
Abstract: An efficient synthesis of 4-arylidene-3-alkylisoxazole-5(4H)-ones has been implemented via the three-component cyclocondensation of aryl(heteroaryl)aldehydes with hydroxylamine hydrochloride and β-ketoesters. The potassium 2,5-dioxoimidazolidin-1-ide has been introduced as the new organocatalyst to facilitate this heterocyclization. In the… read more here.
Keywords: dioxoimidazolidin ide; potassium dioxoimidazolidin; three component; synthesis arylidene ... See more keywords