Design and Synthesis of 5‐Substituted Benzo[d][1,3]dioxole Derivatives as Potent Anticonvulsant Agents
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DOI: 10.1002/ardp.201600274
Abstract: A series of 5‐substituted benzo[d][1,3]dioxole derivatives was designed, synthesized, and tested for anticonvulsant activity using the maximal electroshock (MES) and subcutaneous pentylenetetrazole (scPTZ) screens. Neurotoxicity was determined by rotarod test. In the preliminary screening, six… read more here.
Keywords: design synthesis; derivatives potent; synthesis substituted; dioxole derivatives ... See more keywords