Indoleamine 2,3‐dioxygenase and tryptophan 2,3‐dioxygenase expression in HPV infection, SILs, and cervical cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22172
Abstract: Human papillomavirus (HPV) infection is the central factor for cervical cancer, whereas epithelial immune mechanisms contribute to the progression of HPV infection and its associated lesions. The authors evaluated the expression of indoleamine 2,3‐dioxygenase (IDO)… read more here.
Keywords: cancer; dioxygenase; cervical cancer; hpv infection ... See more keywords
Quercetin attenuates cyclophosphamide induced‐immunosuppressive indoleamine 2,3‐dioxygenase in the hippocampus and cerebral cortex of male Wister rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23179
Abstract: This study investigated the protective effect of quercetin against cyclophosphamide‐induced immunosuppressive indoleamine 2,3‐dioxygenase (IDO) via the mechanism of oxidative‐inflammatory stress and behavioral indices. Cyclophosphamide (CYP) was administered to male Wister rats at a dose of… read more here.
Keywords: cerebral cortex; wister rats; male wister; dioxygenase ... See more keywords
On how the binding cavity of AsqJ dioxygenase controls the desaturation reaction regioselectivity: a QM/MM study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biological Inorganic Chemistry"
DOI: 10.1007/s00775-018-1575-3
Abstract: The Fe(II)/2-oxoglutarate-dependent dioxygenase AsqJ from Aspergillus nidulans catalyses two pivotal steps in the synthesis of quinolone antibiotic 4′-methoxyviridicatin, i.e., desaturation and epoxidation of a benzodiazepinedione. The previous experimental results signal that, during the desaturation reaction,… read more here.
Keywords: binding cavity; desaturation reaction; reaction; dioxygenase ... See more keywords
Thiol dioxygenase turnover yields benzothiazole products from 2-mercaptoaniline and O2-dependent oxidation of primary alcohols.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2017.08.013
Abstract: Thiol dioxygenases are non-heme mononuclear iron enzymes that catalyze the O2-dependent oxidation of free thiols (-SH) to produce the corresponding sulfinic acid (-SO2-). Previous chemical rescue studies identified a putative FeIII-O2- intermediate that precedes substrate… read more here.
Keywords: thiol dioxygenase; dependent oxidation; oxidation; primary alcohols ... See more keywords
Phenol degradation and genotypic analysis of dioxygenase genes in bacteria isolated from sediments
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian Journal of Microbiology"
DOI: 10.1016/j.bjm.2016.12.002
Abstract: The aerobic degradation of aromatic compounds by bacteria is performed by dioxygenases. To show some characteristic patterns of the dioxygenase genotype and its degradation specificities, twenty-nine gram-negative bacterial cultures were obtained from sediment contaminated with… read more here.
Keywords: degradation; dioxygenase; catechol dioxygenase; dioxygenase gene ... See more keywords
Microtubule inhibitors containing immunostimulatory agents promote cancer immunochemotherapy by inhibiting tubulin polymerization and tryptophan-2,3-dioxygenase.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111949
Abstract: A combination therapeutic regimen via introducing tryptophan 2,3-dioxygenase inhibitors into microtubule inhibitors was performed and evaluated for their antitumor activity. Thereinto, HT2, composed of combretastatin A-4 (CA-4) and tryptophan-2,3-dioxygenase (TDO) inhibitor by a linker, displayed… read more here.
Keywords: microtubule inhibitors; tubulin polymerization; tryptophan dioxygenase; cancer ... See more keywords
Bacterial melanin production by heterologous expression of 4‑hydroxyphenylpyruvate dioxygenase from Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.04.061
Abstract: Pyomelanin is a reddish-brown pigment produced by bacteria of different genera and plays a variety of physiological roles. Proposals have been regarding the use of pyomelanin in various environmental, industrial and, more recently, cosmetic applications.… read more here.
Keywords: pseudomonas aeruginosa; production; melanin; pyomelanin ... See more keywords
Inherent allergic potential of α-dioxygenase fragment: A pathogenesis related protein.
Sign Up to like & getrecommendations! Published in 2019 at "Immunobiology"
DOI: 10.1016/j.imbio.2018.11.006
Abstract: In the course of analyzing amino acid sequence of an allergen (≈20 kDa), we found this protein has a homology with the amino acid sequence of putative α-Dioxygenase fragment (ADF). Allergy caused by many allergens having… read more here.
Keywords: allergic potential; balb mice; dioxygenase; dioxygenase fragment ... See more keywords
THE AUTOIMMUNE RESPONSE ELICITED BY MOUSE HEPATITIS VIRUS (MHV-A59) INFECTION IS MODULATED BY LIVER TRYPTOPHAN-2,3-DIOXYGENASE (TDO).
Sign Up to like & getrecommendations! Published in 2019 at "Immunology letters"
DOI: 10.1016/j.imlet.2019.11.004
Abstract: In a previous work we demonstrated that inhibition of mouse indoleamine 2,3-dioxygenase (IDO) by methyltryptophan (MT) exacerbated the pathological actions of mouse hepatitis virus (MHV-A59) infection, suggesting that tryptophan (TRP) catabolism was involved in viral… read more here.
Keywords: infection; tdo; mouse hepatitis; dioxygenase ... See more keywords
Indoleamine 2,3-dioxygenase and trophoblast invasion in caesarean scar pregnancy: Implications for the aetiopathogenesis of placenta accreta spectrum.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2020.103099
Abstract: Immunohistochemical localisation of indoleamine 2,3-dioxygenase was studied in order to better understand the pathophysiology of placenta accreta spectrum. In the decidua staining for indoleamine 2,3-dioxygenase was found in the glandular epithelium with some additional positive… read more here.
Keywords: accreta spectrum; trophoblast invasion; dioxygenase; indoleamine dioxygenase ... See more keywords
Expression and characterization of catechol 1,2-dioxygenase from Oceanimonas marisflavi 102-Na3.
Sign Up to like & getrecommendations! Published in 2021 at "Protein expression and purification"
DOI: 10.1016/j.pep.2021.105964
Abstract: The gene of catechol 1, 2-dioxygenase was identified and cloned from the genome of Oceanimonas marisflavi 102-Na3. The protein was expressed in Escherichia coli BL21 (DE3) and purified to homogeneity of a dimer with molecular… read more here.
Keywords: oceanimonas marisflavi; catechol dioxygenase; 102 na3; marisflavi 102 ... See more keywords