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Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220718155616
Abstract: BACKGROUND Indoleamine 2,3-dioxygenase (IDO) activity is induced by cellular immune activation and therefore associated to inflammatory diseases, among others psychiatric disorders. This review aims to elucidate IDO activity reflected by kynurenine (KYN) to tryptophan (TRP)…
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Keywords:
ido;
kyn trp;
indoleamine dioxygenase;
dioxygenase ido ... See more keywords
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Published in 2020 at "Diagnostics"
DOI: 10.3390/diagnostics10050275
Abstract: Indolamine-2,3-dioxygenase (IDO) is an intracellular enzyme that catalyzes amino acid tryptophan to L-kynurenine. IDO is overexpressed in various cancers and several IDO inhibitors have been assessed in multiple clinical trials. If an IDO inhibitor is…
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Keywords:
ido;
various types;
dioxygenase ido;
types lymphoma ... See more keywords