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Published in 2019 at "Expert Opinion on Therapeutic Patents"
DOI: 10.1080/13543776.2019.1556638
Abstract: ABSTRACT Introduction: Tryptophan-2, 3-dioxygenase (TDO2) is a tryptophan-degrading enzyme constitutively expressed in the liver and to a lesser extend in the brain. Before its link to cancer immunotherapy was discovered in 2011, the search for…
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Keywords:
dioxygenase inhibitors;
current state;
state tryptophan;
tryptophan dioxygenase ... See more keywords