Articles with "dioxygenase inhibitors" as a keyword



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Current state on tryptophan 2,3-dioxygenase inhibitors: a patent review

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Published in 2019 at "Expert Opinion on Therapeutic Patents"

DOI: 10.1080/13543776.2019.1556638

Abstract: ABSTRACT Introduction: Tryptophan-2, 3-dioxygenase (TDO2) is a tryptophan-degrading enzyme constitutively expressed in the liver and to a lesser extend in the brain. Before its link to cancer immunotherapy was discovered in 2011, the search for… read more here.

Keywords: dioxygenase inhibitors; current state; state tryptophan; tryptophan dioxygenase ... See more keywords