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Published in 2021 at "Synlett"
DOI: 10.1055/a-1545-2860
Abstract: An efficient three-step synthesis towards 3-amino-1,4-benzodiazepin-2-one derivatives is presented. The versatile Ugi-4-component reaction (Ugi-4CR) and Boc deprotection is followed by a ligand-free Ullmann condensation. This protocol allows the rapid construction of a diverse array of…
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Keywords:
dipeptide mimetics;
synthesis;
ugi 4cr;
ullmann condensation ... See more keywords
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Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15030284
Abstract: Neurotrophins are considered as an attractive target for the development of antidepressants with a novel mechanism of action. Previously, the dimeric dipeptide mimetics of individual loops of nerve growth factor, NGF (GK-6, loop 1; GK-2,…
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Keywords:
gsb 106;
dipeptide mimetics;
loop;
antidepressant like ... See more keywords