Articles with "dipeptide nitrile" as a keyword



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Dipeptide Nitrile CD34 with Curcumin: A New Improved Combination Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24108477

Abstract: Rhodesain is the main cysteine protease of Trypanosoma brucei rhodesiense, the parasite causing the acute lethal form of Human African Trypanosomiasis. Starting from the dipeptide nitrile CD24, the further introduction of a fluorine atom in… read more here.

Keywords: brucei rhodesiense; trypanosoma brucei; combination; dipeptide nitrile ... See more keywords