Culture methods of diffuse intrinsic pontine glioma cells determine response to targeted therapies
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DOI: 10.1016/j.yexcr.2017.09.032
Abstract: Abstract Diffuse intrinsic pontine glioma (DIPG) is an aggressive type of brainstem cancer occurring mainly in children, for which there currently is no effective therapy. Current efforts to develop novel therapeutics for this tumor make… read more here.
Keywords: response; dipg cells; culture conditions; culture ... See more keywords
Abstract B05: Mechanisms of PPM1D-mediated tumorigenesis in diffuse intrinsic pontine glioma (DIPG)
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DOI: 10.1158/1538-7445.pedca17-b05
Abstract: Diffuse intrinsic pontine glioma (DIPG), the most common pediatric brainstem tumor, is associated with a dismal prognosis with almost no survivors within two years of diagnosis. It is unamenable to surgical resection, is not responsive… read more here.
Keywords: inhibition; dipg cells; proliferation; ppm1d ... See more keywords