Synthesis and Cytotoxic Activity of Lepidilines A-D: Comparison with Some 4,5-Diphenyl Analogues and Related Imidazole-2-thiones.
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DOI: 10.1021/acs.jnatprod.1c00797
Abstract: A straightforward access to 2-unsubstituted imidazole N-oxides with subsequent deoxygenation by treatment with Raney-nickel followed by N-benzylation opens up a convenient route to lepidilines A and C. Both imidazolium salts were used to generate in… read more here.
Keywords: imidazole thiones; diphenyl analogues; synthesis cytotoxic; activity ... See more keywords