Diphenyl diselenide ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats via suppressing oxidative stress and inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109427
Abstract: Oxidative stress and inflammation are implicated in the occurrence and progression of diabetic nephropathy (DN). Diphenyl diselenide (DPDS) is a stable and simple diaryl diselenide with anti-hyperglycemic, anti-inflammatory, and antioxidant activities. However, the effects of… read more here.
Keywords: diphenyl diselenide; stress inflammation; stress; diabetic nephropathy ... See more keywords
Diphenyl diselenide suppresses key virulence factors of Candida krusei, a neglected fungal pathogen
Sign Up to like & getrecommendations! Published in 2022 at "Biofouling"
DOI: 10.1080/08927014.2022.2084388
Abstract: Abstract Candida krusei is a candidiasis etiological agent of relevance in the clinical setting because of its intrinsic resistance to fluconazole. Also, it has opened up new paths in the area of alternative therapeutic techniques.… read more here.
Keywords: diphenyl diselenide; candida krusei; virulence factors; krusei ... See more keywords
p-Chloro-diphenyl diselenide attenuates plasma lipid profile changes and hepatotoxicity induced by nonionic surfactant tyloxapol in rats
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2019.1669240
Abstract: Abstract Tyloxapol is a nonionic surfactant oligomer inductor of dyslipidemia, which in turn is a risk factor for liver damage. Selenium-based compounds have emerged as promising therapeutic candidates for treating different experimental disorders. This study… read more here.
Keywords: chloro diphenyl; diphenyl diselenide; tyloxapol; plasma lipid ... See more keywords
Effectiveness of Diphenyl Diselenide against Experimental Sporotrichosis caused by Sporothrix brasiliensis.
Sign Up to like & getrecommendations! Published in 2023 at "Medical mycology"
DOI: 10.1093/mmy/myad035
Abstract: Diphenyl diselenide (PhSe)2 is a stable organoselenium compound with promising in vitro antifungal activity against several fungi, including Sporothrix brasiliensis. This species is associated with feline and zoonotic sporotrichosis, an emergent mycosis in Latin America.… read more here.
Keywords: sporotrichosis; phse; brasiliensis; sporothrix brasiliensis ... See more keywords
p-Chloro-diphenyl diselenide modulates Nrf2/Keap1 signaling and counteracts renal oxidative stress in mice exposed to dexamethasone repeated administrations.
Sign Up to like & getrecommendations! Published in 2022 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2021-0573
Abstract: Dexamethasone is a synthetic glucocorticoid that has been associated with oxidative stress in central and peripheral tissues. p-Chloro-diphenyl diselenide (p-ClPhSe)2 is an antioxidant organoselenium compound. The present study aimed to evaluate whether Nrf2/Keap-1 signaling contributes… read more here.
Keywords: diphenyl diselenide; mice exposed; oxidative stress; exposed dexamethasone ... See more keywords
Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period.
Sign Up to like & getrecommendations! Published in 2019 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765201920171042
Abstract: The aims of this study were to investigate whether treatments with zinc edetate (Zn) and diphenyl diselenide ((PhSe)2) enhance performance, immune responses, protein metabolism, and oxidant/antioxidant status in calf serum and muscle. Animals were divided… read more here.
Keywords: zinc edetate; diphenyl diselenide; phse; edetate diphenyl ... See more keywords
Swimming exercise and diphenyl diselenide-supplemented diet modulate cerebral cortical and striatal GABA uptake in aged rats.
Sign Up to like & getrecommendations! Published in 2022 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202220200844
Abstract: Aging is characterized by several neurochemical modifications involving structural proteins and neurotransmitters. Exercise has been recognized as an enhancer of overall health; whereas, diphenyl diselenide (PhSe)2 has been reported to have antioxidant, anti-inflammatory, and neuroprotective… read more here.
Keywords: uptake aged; swimming exercise; aged rats; diphenyl diselenide ... See more keywords
Diphenyl Diselenide – catalyzed Reductive Coupling of Nitroarenes to Aromatic Azo and Azoxy Compounds with Sodium Borohydride in Alkaline Ethanol
Sign Up to like & getrecommendations! Published in 2018 at "Current Organic Synthesis"
DOI: 10.2174/1570179415666181025151130
Abstract: Aim and Objective: A simple catalytic method has been developed to achieve the reduction of nitroarenes with NaBH4 using diphenyl diselenide catalyst in order to obtain the azoxyarene, azoarene products under mild conditions. The reduction… read more here.
Keywords: diphenyl diselenide; borohydride alkaline; azoxy compounds; sodium borohydride ... See more keywords
In Vitro Activity of Ebselen and Diphenyl Diselenide Alone and in Combination with Drugs against Trichophyton mentagrophytes Strains
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14061158
Abstract: Background: Dermatophytoses are one of the most prevalent infectious diseases in the world for which the pace of developing new drugs has not kept pace with the observed therapeutic problems. Thus, searching for new antifungals… read more here.
Keywords: ebselen diphenyl; combination; activity; diphenyl diselenide ... See more keywords