Human CYP enzyme-activated clastogenicity of 2-ethylhexyl diphenyl phosphate (a flame retardant) in mammalian cells.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.117527
Abstract: 2-Ethylhexyl diphenyl phosphate (EHDPP) is a common flame retardant and environmental pollutant, exposing humans with endocrinal disrupting potentials. Its mutagenicity, especially following metabolism, remains unclear. In this study, molecular docking analysis indicated that EHDPP was… read more here.
Keywords: cyp; diphenyl phosphate; flame retardant; human cyp ... See more keywords
First Insight into the Formation of In Vivo Transformation Products of 2-Ethylhexyl diphenyl phosphate in Zebrafish and Prediction of Their Potential Toxicities.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c05506
Abstract: As a frequently detected organophosphorus flame retardant in the environment, 2-ethylhexyl diphenyl phosphate (EHDPHP) is vulnerable to biotransformation, while the transformation mechanisms and potential toxicities of its transformation products remain unclear. In the present study,… read more here.
Keywords: ethylhexyl diphenyl; diphenyl phosphate; ehdphp; transformation products ... See more keywords
Biotransformation of bisphenol-A bis(diphenyl phosphate): In vitro, in silico, and (non-) target analysis for metabolites in rat and bird liver microsomal models.
Sign Up to like & getrecommendations! Published in 2022 at "Chemosphere"
DOI: 10.2139/ssrn.4211174
Abstract: Increased production and usage of organophosphate esters (OPEs) as flame retardants and plasticizers has trended towards larger and 'novel' (oligomeric) OPEs, although there is a dearth of understanding of the environmental fate, stability, toxicokinetics, biotransformation… read more here.
Keywords: phosphate; diphenyl phosphate; non target; biotransformation ... See more keywords