From benchtop to pilot scale-experimental study and computational assessment of a hot-melt extrusion scale-up of a solid dispersion of dipyridamole and copovidone.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.12.033
Abstract: The aim of our work was to study and define a computationally-based adiabatic scale-up methodology for a hot-melt extrusion (HME) process to produce an amorphous solid dispersion (ASD). As a drug product becomes commercially viable,… read more here.
Keywords: melt extrusion; solid dispersion; hot melt; dipyridamole copovidone ... See more keywords