Cu-Catalyzed Coupling of O-Acyl Oximes with Isatins: Domino Rearrangement Strategy for Direct Access to Quinoline-4-Carboxamides by C-N Bond Cleavage
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201800501
Abstract: A mild domino rearrangement strategy for the direct access to substituted quinoline‐4‐carboxamides has been developed. This copper‐catalyzed coupling reaction of O‐acyl oximes with isatins in the presence of molecular oxygen as the sole oxidizing agent… read more here.
Keywords: strategy direct; quinoline carboxamides; domino rearrangement; direct access ... See more keywords
Do direct-access and indirect-access adaptation projects differ in their focus on local communities? A systematic analysis of 63 Adaptation Fund projects
Sign Up to like & getrecommendations! Published in 2020 at "Regional Environmental Change"
DOI: 10.1007/s10113-020-01716-4
Abstract: Recent literature suggests that direct national access to multilateral climate funds could promote climate change adaptation investment that focuses more on the needs of vulnerable local communities when compared to indirect access through multilateral agencies.… read more here.
Keywords: community; direct access; access indirect; indirect access ... See more keywords
Direct access to highly crystalline mesoporous nano TiO2 using sterically bulky organic acid templates
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Physics and Chemistry of Solids"
DOI: 10.1016/j.jpcs.2018.01.043
Abstract: Abstract Sterically bulky monocarboxylic acid templates pivalic acid and phenoxyacetic acid are reported for the first time as organic templates in the sol-gel synthesis of TiO2. Mesoporous nanoparticulates of pure anatase phase and of well… read more here.
Keywords: tio2; sterically bulky; acid templates; direct access ... See more keywords
2-Nitrodiphenylalkanes/alkenes as adept photosynthons for direct access to valuable N-heterocycles
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Photochemistry and Photobiology A: Chemistry"
DOI: 10.1016/j.jphotochem.2019.02.014
Abstract: Abstract Photoexcited o-nitro chromophore in o-nitrobenzylic systems has led to the design and development of many useful photochromic systems such as photolabile protecting groups, photoresists, for controlled release of bioactive compounds, as well as efficient… read more here.
Keywords: alkenes adept; adept photosynthons; photosynthons direct; nitrodiphenylalkanes alkenes ... See more keywords
Providing patients with direct access to musculoskeletal physiotherapy: the impact on general practice musculoskeletal workload and resource use. The STEMS-2 study
Sign Up to like & getrecommendations! Published in 2020 at "Physiotherapy"
DOI: 10.1016/j.physio.2020.04.006
Abstract: Objectives This study examined the real-world impact of patient direct access to NHS physiotherapy (self-referral) on (a) general practice consultations for musculoskeletal (MSK) conditions and (b) specified clinical management for patients with MSK conditions. Design… read more here.
Keywords: general practice; self referral; impact; direct access ... See more keywords
Implementing patient direct access to musculoskeletal physiotherapy in primary care: views of patients, general practitioners, physiotherapists and clinical commissioners in England
Sign Up to like & getrecommendations! Published in 2020 at "Physiotherapy"
DOI: 10.1016/j.physio.2020.07.002
Abstract: Purpose Musculoskeletal problems are the leading cause of chronic disability. Most patients in the UK seek initial care from general practitioners (GPs), who are struggling to meet demand. Patient direct access to National Health Service… read more here.
Keywords: general practitioners; patient direct; direct access; physiotherapy ... See more keywords
Economic evaluation of patient direct access to NHS physiotherapy services.
Sign Up to like & getrecommendations! Published in 2021 at "Physiotherapy"
DOI: 10.1016/j.physio.2020.12.005
Abstract: OBJECTIVES Our aim was to undertake an economic evaluation of patient direct access to physiotherapy in the UK NHS by comparing the number of patients treated, waiting time, cost and health gain from a direct… read more here.
Keywords: direct access; physiotherapy; physiotherapy services; evaluation patient ... See more keywords
Thiophene ring-opening reactions. Direct access to the synthesis of 1,3,4-thiadiazoline-(condenced) pyridone hybrids
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DOI: 10.1016/j.tet.2021.131957
Abstract: Abstract The reaction of N’-(aryl)benzothiohydrazides with 2-chloro-7-cyclopropyl-3-nitro-4-oxothieno[2,3-b]pyridine-5-carboxylic ester/acid in the presence of triethylamine furnished, upon addition of iodomethane, the respective 1,3,4-thiadiazoline-(6-methylthio-4-oxopyridine) hybrids. Interestingly, the reaction of thiohydrazides with 4-oxothieno[2,3-b]pyridines incorporating N1-(2’-halogeno-5’-nitrophenyl) entities generated 1,3-thiazoline ring… read more here.
Keywords: opening reactions; thiadiazoline; thiophene ring; direct access ... See more keywords
Aminoalkylation of [1.1.1]Propellane Enables Direct Access to High-Value 3-Alkylbicyclo[1.1.1]pentan-1-amines.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02426
Abstract: Bicyclo[1.1.1]pentanes are effective bioisoteres for aromatic rings, tert-butyl groups, and alkynes. Here we report the first method to synthesize 3-alkylbicyclo[1.1.1]pentan-1-amines directly from [1.1.1]propellane via sequential addition of magnesium amides and alkyl electrophiles. The mild reaction… read more here.
Keywords: aminoalkylation propellane; pentan amines; direct access; enables direct ... See more keywords
Direct access to substituted benzo[b]carbazoles through cascade annulation of 2-vinylbenzaldehydes with indoles.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c8cc10253h
Abstract: A highly efficient palladium-catalyzed cascade annulation of 2-vinylbenzaldehydes with indoles has been achieved to afford 6-(3-indolyl)benzo[b]carbazoles under mild conditions in good yield and with excellent regioselectivity. Mechanistic investigations reveal that the reaction proceeds via double… read more here.
Keywords: vinylbenzaldehydes indoles; direct access; benzo carbazoles; annulation vinylbenzaldehydes ... See more keywords
Direct access to thieno[3,4-b]thiophenes via elemental sulfur-promoted sulfurative tetramerization of acetophenones.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc05539b
Abstract: Thieno[3,4-b]thiophene cores could be conveniently obtained via one-pot sulfurative tetramerization of acetophenones using a ternary system comprised of elemental sulfur, a base and DMSO under simple heating conditions. The structure of the products was verified… read more here.
Keywords: sulfurative tetramerization; direct access; tetramerization acetophenones; elemental sulfur ... See more keywords