Expanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2019.4748
Abstract: Importance For patients awaiting heart transplant, hepatitis C-positive donors offer an opportunity to expand the donor pool, shorten wait times, and decrease wait-list mortality. While early reported outcomes among few heart transplant recipients have been… read more here.
Keywords: hepatitis; transplant; direct acting; heart transplant ... See more keywords
Hepatocellular carcinoma after a sustained virological response by direct‐acting antivirals harbors TP53 inactivation
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4571
Abstract: The genomic characteristics of hepatocellular carcinoma (HCC) after a sustained virological response (SVR) and its differences according to whether an SVR was achieved by treatment with direct‐acting antivirals (DAA) or interferon (IFN) are still not… read more here.
Keywords: sustained virological; hepatocellular carcinoma; acting antivirals; direct acting ... See more keywords
Reduction in liver transplant wait‐listing in the era of direct‐acting antiviral therapy
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DOI: 10.1002/hep.28923
Abstract: Direct‐acting antiviral (DAA) therapy, recently approved for patients with decompensated cirrhosis (DC) secondary to hepatitis C virus (HCV), is associated with improved hepatic function. We analyzed trends in liver transplant (LT) wait‐listing (WL) to explore… read more here.
Keywords: era; daa; direct acting; acting antiviral ... See more keywords
Stratification of Residual Risk of HCC Following HCV Clearance With Direct‐Acting Antivirals in Patients With Advanced Fibrosis and Cirrhosis
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DOI: 10.1002/hep.31639
Abstract: Hepatitis C virus (HCV) is a major risk factor for hepatocellular carcinoma (HCC), one of the deadliest cancers with increasing incidence over the past few decades (1). Direct-acting antiviral (DAA) therapy in HCV-infected patients has… read more here.
Keywords: risk; hcc; cirrhosis; direct acting ... See more keywords
Reply: "Recurrent cryoglobulinemic vasculitis in the era of direct acting antivirals: A story beyond SVR 12."
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31861
Abstract: We would like to thank Dr. Roy and Dr. Dhiman for the interest in our study. Their comments stressed two primary aspects regarding the management of patients with HCV chronic infection. read more here.
Keywords: era direct; vasculitis era; reply recurrent; direct acting ... See more keywords
Machine learning algorithms for predicting direct‐acting antiviral treatment failure in chronic hepatitis C: An HCV‐TARGET analysis
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DOI: 10.1002/hep.32347
Abstract: We aimed to develop and validate machine learning algorithms to predict direct‐acting antiviral (DAA) treatment failure among patients with HCV infection. read more here.
Keywords: learning algorithms; machine learning; treatment failure; direct acting ... See more keywords
DIRECT‐ACTING ANTIVIRALS DURING OR AFTER IMMUNO‐CHEMOTHERAPY IN HEPATITIS C VIRUS‐ASSOCIATED DIFFUSE LARGE B‐CELL LYMPHOMAS
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DOI: 10.1002/hon.2438_57
Abstract: vs 10.7%, p = 0.18) GVHD were also comparable as well as 2‐year GVHD free/relapse‐free survival (FB2: 44.4% vs 42.8%, p = 0.38). In multivariate analysis, there was a trend for worse outcome using FB3/FB4… read more here.
Keywords: chemotherapy hepatitis; direct acting; antivirals immuno; hepatitis virus ... See more keywords
Amino acid substitutions in the hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by all‐oral direct‐acting antiviral regimens
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25047
Abstract: Impact of substitution of aa70 in the core region (Core aa70) in HCV genotype 1b (HCV‐1b) on hepatocarcinogenesis following eradication of HCV RNA by direct‐acting antiviral therapy is not clear. In a retrospective study, 533… read more here.
Keywords: hcv rna; direct acting; acting antiviral; hepatocarcinogenesis ... See more keywords
Improvement of liver stiffness measurement, acoustic radiation force impulse measurements, and noninvasive fibrosis markers after direct‐acting antivirals for hepatitis C virus G4 recurrence post living donor liver transplantation: Egyptian cohort
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25210
Abstract: Progression of recurrent hepatitis C is accelerated in liver transplant (LT) recipients. Direct‐acting antivirals (DAAs) have recently emerged as a promising therapeutic regimen for the treatment of hepatitis C virus infection. Rates of sustained virological… read more here.
Keywords: improvement; fibrosis; recurrence; elastography ... See more keywords
The effects of direct‐acting antiviral agents on the frequency of myeloid‐derived suppressor cells and natural killer cells in patients with chronic hepatitis C
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25302
Abstract: Currently, hepatitis C antiviral therapy is entering a new era with the use of direct‐acting antiviral (DAA) agents. However, the precise immunological influences of DAA therapy in patients with chronic hepatitis C (CHC) are insufficiently… read more here.
Keywords: hepatitis; frequency; direct acting; acting antiviral ... See more keywords
Direct‐acting antiviral agents in the treatment of chronic hepatitis C—Real‐life experience from clinical practices in Pakistan
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25745
Abstract: This study aims to evaluate the clinical effectiveness in terms of sustained virological response (SVR), predictors of SVR and safety of available second‐generation generic direct‐acting antivirals in Pakistani chronic hepatitis C patients. This is a… read more here.
Keywords: daclatasvir; treatment; genotype; direct acting ... See more keywords