Quantum Dots Photocatalysis Enabled Direct Activation of Acetone for Radical‐Radical Cross‐Coupling
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202502878
Abstract: In 2023, the Nobel Prize in Chemistry is awarded to Moungi G. Bawendi, Louis E. Brus, and Alexei I. Ekimov for the discovery and synthesis of quantum dots (QDs). Herein, a single QDs is demonstrated for… read more here.
Keywords: dots photocatalysis; activation; direct activation; activation acetone ... See more keywords
Direct Activation of Unmodified Morita-Baylis-Hillman Alcohols through Phosphine Catalysis for Rapid Construction of Three-Dimensional Heterocyclic Compounds.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01783
Abstract: The phosphine-catalyzed tandem annulation reaction of Morita-Baylis-Hillman (MBH) alcohols with azomethine imines has been achieved for the synthesis of biologically important (epoxymethano)-pyrazolo[5,1- b]quinazoline derivatives. A variety of MBH alcohols and azomethine imines were well-tolerated under… read more here.
Keywords: morita baylis; heterocyclic compounds; baylis hillman; direct activation ... See more keywords
Asymmetric Three-Component Radical Alkene Carboazidation by Direct Activation of Aliphatic C-H Bonds.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c02012
Abstract: Azide compounds are widely present in natural products and drug molecules, and their easy-to-transform characteristics make them widely used in the field of organic synthesis. The merging of transition-metal catalysis with radical chemistry offers a… read more here.
Keywords: carboazidation; activation aliphatic; three component; direct activation ... See more keywords
Direct activation of zebrafish neurons by ultrasonic stimulation revealed by whole CNS calcium imaging.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/abae8b
Abstract: OBJECTIVE Ultrasounds (US) use in neural engineering is so far mainly limited to ablation through high intensity focused ultrasound, but interesting preliminary results show that low intensity low frequency ultrasound could be used instead to… read more here.
Keywords: response; stimulation; direct activation; calcium imaging ... See more keywords
Impaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Diabetology"
DOI: 10.1186/s12933-024-02321-z
Abstract: Glucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) with nuclear sequestration at low plasma glucose level. Some GK activators (GKAs) disrupt GK-GKRP interaction… read more here.
Keywords: direct activation; impaired gkrp; mendelian randomization; interaction ... See more keywords
Direct activation of HSF1 by macromolecular crowding and misfolded proteins
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0312524
Abstract: Stress responses play a vital role in cellular survival against environmental challenges, often exploited by cancer cells to proliferate, counteract genomic instability, and resist therapeutic stress. Heat shock factor protein 1 (HSF1), a central transcription… read more here.
Keywords: activation hsf1; stress; hsf1; protein ... See more keywords