DW14006 as a direct AMPKα1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
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DOI: 10.1016/j.bbi.2020.07.041
Abstract: Alzheimer's disease (AD) is a progressively neurodegenerative disease with typical hallmarks of amyloid β (Aβ) plaque accumulation, neurofibrillary tangle (NFT) formation and neuronal death extension. In AD brain, activated microglia phagocytose Aβ and neuronal debris,… read more here.
Keywords: direct ampk; ampk activator; pathology; ampk ... See more keywords