Determining direct binders of the Androgen Receptor using a high-throughput Cellular Thermal Shift Assay
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DOI: 10.1038/s41598-017-18650-x
Abstract: Androgen Receptor (AR) is a key driver in prostate cancer. Direct targeting of AR has valuable therapeutic potential. However, the lack of disease relevant cellular methodologies capable of discriminating between inhibitors that directly bind AR… read more here.
Keywords: direct binders; shift assay; cellular thermal; receptor ... See more keywords