Deterministic Single Cell Encapsulation in Asymmetric Microenvironments to Direct Cell Polarity
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DOI: 10.1002/advs.202206014
Abstract: Various signals in tissue microenvironments are often unevenly distributed around cells. Cellular responses to asymmetric cell‐matrix adhesion in a 3D space remain generally unclear and are to be studied at the single‐cell resolution. Here, the… read more here.
Keywords: cell; presentation; cell polarity; single cell ... See more keywords
Proteomics Analysis Identifies IRSp53 and Fascin as Critical for PRV Egress and Direct Cell–Cell Transmission
Sign Up to like & getrecommendations! Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201900009
Abstract: Pseudorabies virus (PRV) has been widely used as a live trans‐synaptic tracer for mapping neuronal circuits. Systematically identifying mature PRV virion proteomes and defining co‐purified host proteins are necessary to fully understand the detailed mechanism… read more here.
Keywords: transmission; prv; fascin critical; irsp53 fascin ... See more keywords
Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging
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DOI: 10.1021/acs.chemrev.1c00767
Abstract: The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical application in a rational manner depends on reliable, clinically applicable methods for determining the fate and trafficking of therapeutic cells in… read more here.
Keywords: cell tracking; cell; vivo cell; radiolabeling vivo ... See more keywords
Direct Cell Conversion of Somatic Cells into Dopamine Neurons: Achievements and Perspectives.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular reprogramming"
DOI: 10.1089/cell.2022.0065
Abstract: In the last decade, direct reprogramming has emerged as a novel strategy to obtain mature and functional dopamine neurons from somatic cells. This approach could overcome issues linked to the use of human pluripotent stem… read more here.
Keywords: conversion somatic; conversion; somatic cells; dopamine neurons ... See more keywords
Computational approaches for direct cell reprogramming: from the bulk omics era to the single cell era
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Functional Genomics"
DOI: 10.1093/bfgp/elac008
Abstract: Abstract Recent advances in direct cell reprogramming have made possible the conversion of one cell type to another cell type, offering a potential cell-based treatment to many major diseases. Despite much attention, substantial roadblocks remain… read more here.
Keywords: cell; transcription; single cell; transcription factor ... See more keywords
Direct T-cell Presentation by cDC1: The Key Feature for Cancer Vaccine Success?
Sign Up to like & getrecommendations! Published in 2022 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-22-0473
Abstract: In this issue of Cancer Immunology Research, Ferris and colleagues demonstrate that type 1 conventional DC (cDC1) vaccines drive tumor rejection through direct antigen presentation, without the need of endogenous cDC1. This suggests that cDC1-based… read more here.
Keywords: cdc1; cell presentation; direct cell; cancer ... See more keywords
Direct cell reprogramming for tissue engineering and regenerative medicine
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biological Engineering"
DOI: 10.1186/s13036-019-0144-9
Abstract: Direct cell reprogramming, also called transdifferentiation, allows for the reprogramming of one somatic cell type directly into another, without the need to transition through an induced pluripotent state. Thus, it is an attractive approach to… read more here.
Keywords: medicine; engineering; cell reprogramming; tissue ... See more keywords
Direct Cell–Cell Interactions in the Endometrium and in Endometrial Pathophysiology
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DOI: 10.3390/ijms19082227
Abstract: Cell contacts exhibit a considerable influence on tissue physiology and homeostasis by controlling paracellular and intercellular transport processes, as well as by affecting signaling pathways. Since they maintain cell polarity, they play an important role… read more here.
Keywords: cell interactions; cell cell; interactions endometrium; direct cell ... See more keywords
The effect of direct cell injury inflicted by cryotherapy on eyelid sebaceous gland carcinoma cells: An ex-vivo experimental study
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_1814_21
Abstract: Purpose: To evaluate the effect of direct cell injury of cryotherapy on eyelid sebaceous gland carcinoma cells by an ex vivo cryotherapy experiment. Methods: It was a prospective interventional case series. Six patients with biopsy-proven… read more here.
Keywords: sebaceous gland; direct cell; gland carcinoma; cell injury ... See more keywords