Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.4782
Abstract: Key Points Question Is the recent use of direct oral anticoagulants (confirmed ingestion within 48 hours) associated with increased risk of symptomatic intracranial hemorrhage following intravenous thrombolysis for ischemic stroke? Findings In this cohort study… read more here.
Keywords: intravenous thrombolysis; direct oral; patients ischemic; oral anticoagulants ... See more keywords
Cost‐effectiveness analysis of low‐dose direct oral anticoagulant (DOAC) for the prevention of cancer‐associated thrombosis in the United States
Sign Up to like & getrecommendations! Published in 2020 at "Cancer"
DOI: 10.1002/cncr.32724
Abstract: Randomized controlled trials (RCTs) have demonstrated that low‐dose direct oral anticoagulants (DOACs), including rivaroxaban and apixaban, may help reduce the incidence of cancer‐associated venous thromboembolism (VTE). read more here.
Keywords: low dose; direct oral; dose direct; cancer ... See more keywords
Population Pharmacokinetic Models for Direct Oral Anticoagulants: A Systematic Review and Clinical Appraisal Using Exposure Simulation
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2649
Abstract: Available data have shown an association between direct oral anticoagulant (DOAC) plasma concentration and clinical, particularly bleeding, events. Factors that may influence DOAC plasma concentration are therefore the focus of particular attention. Population pharmacokinetic (PopPK)… read more here.
Keywords: plasma concentration; population pharmacokinetic; direct oral; doac plasma ... See more keywords
Impact of direct oral anticoagulant concentration on clinical outcomes in Asian patients with atrial fibrillation.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2927
Abstract: A real-world association between direct oral anticoagulant (DOAC) concentration and clinical outcomes among Asian patients with atrial fibrillation (AF) is reported herein. Patients with AF aged ≥20 years who used DOAC for ≥3 days were enrolled. Trough… read more here.
Keywords: clinical outcomes; oral anticoagulant; concentration; direct oral ... See more keywords
Electrical cardioversion of atrial arrhythmias with cardiac amyloidosis in the era of direct oral anticogulants
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14082
Abstract: Atrial fibrillation (AF)/atrial flutter is common during cardiac amyloidosis (CA). Electrical cardioversion (EC) is a strategy to restore sinus rhythm (SR). However, left atrial thrombus (LAT) represents a contraindication for EC. CA patients with AF/atrial… read more here.
Keywords: direct oral; electrical cardioversion; cardiac amyloidosis; atrial flutter ... See more keywords
Systematic review of efficacy of direct oral anticoagulants and vitamin K antagonists in left ventricular thrombus
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14084
Abstract: Left ventricular thrombus (LVT) increases the risk of thrombotic events and mortality. Vitamin K antagonists (VKAs) used to treat LVT have several known risks, as a result of which direct oral anticoagulant (DOAC) use has… read more here.
Keywords: ventricular thrombus; vitamin antagonists; efficacy; direct oral ... See more keywords
Direct Oral Anticoagulation versus Warfarin in Left Ventricular Thrombus: Pooled Analysis of Randomized Controlled Trials.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2267
Abstract: Patients with impaired left ventricular (LV) function can develop LV thrombus, a potentially life-threatening condition due to risk of stroke and embolization. Conventional treatment with vitamin K antagonists (VKA; e.g., warfarin) puts patients at risk… read more here.
Keywords: randomized controlled; controlled trials; direct oral; thrombus ... See more keywords
Comparison of effectiveness and safety between uninterrupted direct oral anticoagulants with and without switching to dabigatran in atrial fibrillation ablation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12333
Abstract: Recent studies have demonstrated the feasibility of uninterrupted direct oral anticoagulants (DOACs) with a temporary switch to dabigatran (“dabigatran bridge”) for atrial fibrillation (AF) ablation. We compared the effectiveness and safety between uninterrupted DOACs with… read more here.
Keywords: atrial fibrillation; effectiveness safety; oral anticoagulants; direct oral ... See more keywords
Relationship between the degree of renal dysfunction and the safety and efficacy outcomes in patients with atrial fibrillation receiving direct oral anticoagulants
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12493
Abstract: The clinical evaluation of a direct oral anticoagulant (DOAC) treatment for atrial fibrillation (AF) patients with renal dysfunction has not been sufficiently studied. This study aimed to evaluate the safety and efficacy of DOACs for… read more here.
Keywords: atrial fibrillation; renal dysfunction; safety efficacy; direct oral ... See more keywords
Outcomes of uninterrupted vs interrupted Periprocedural direct oral Anticoagulants in atrial Fibrillation ablation: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12507
Abstract: Studies indicate that uninterrupted anticoagulation (UA) is superior to interrupted anticoagulation (IA) in the periprocedural period during catheter ablation of atrial fibrillation. Still IA is followed in many centers considering the bleeding risk. This meta‐analysis… read more here.
Keywords: atrial fibrillation; ablation; direct oral; meta analysis ... See more keywords
Reversal of direct oral anticoagulants for liver transplantation in cirrhosis: A step forward
Sign Up to like & getrecommendations! Published in 2017 at "Liver Transplantation"
DOI: 10.1002/lt.24708
Abstract: Direct oral anticoagulants (DOACs) are increasingly used for the treatment and prevention of venous thromboembolism (VTE), including in patients with liver disease. Dabigatran, a factor IIa inhibitor, is approved for treatment of VTE and to… read more here.
Keywords: vte; reversal; time; direct oral ... See more keywords