Direct protein-lipid interactions shape the conformational landscape of secondary transporters
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DOI: 10.1038/s41467-018-06704-1
Abstract: Secondary transporters undergo structural rearrangements to catalyze substrate translocation across the cell membrane – yet how such conformational changes happen within a lipid environment remains poorly understood. Here, we combine hydrogen-deuterium exchange mass spectrometry (HDX-MS)… read more here.
Keywords: protein lipid; conformational landscape; direct protein; secondary transporters ... See more keywords