Modular Oxidation of Cytosine Modifications and Their Application in Direct and Quantitative Sequencing of 5-Hydroxymethylcytosine
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c01663
Abstract: Selective, efficient, and controllable oxidation of cytosine modifications is valuable for epigenetic analyses, yet only limited progress has been made. Here, we present two modular chemical oxidation reactions: conversion of 5-hydroxymethylcytosine (5hmC) into 5-formylcytosine (5fC)… read more here.
Keywords: oxidation; direct quantitative; oxidation cytosine; cytosine modifications ... See more keywords
Direct and quantitative evaluation of the human CYP3A4 contribution (fm) to drug clearance using the in vitro SILENSOMES model
Sign Up to like & getrecommendations! Published in 2017 at "Xenobiotica"
DOI: 10.1080/00498254.2016.1208854
Abstract: Abstract 1. Among the different in vitro studies recommended by the regulatory agencies, no gold-standard model can easily and directly measure the quantitative CYP450 contributions to drug biotransformation. In this article, we propose an original strategy,… read more here.
Keywords: cyp450; drug; clearance; cyp3a4 ... See more keywords
Direct quantitative photoacoustic tomography for realistic acoustic media
Sign Up to like & getrecommendations! Published in 2019 at "Inverse Problems"
DOI: 10.1088/1361-6420/ab091e
Abstract: Quantitative photo-acoustic tomography (QPAT) seeks to reconstruct a distribution of optical attenuation coefficients inside a sample from a set of time series of pressure data that is measured outside the sample. The associated inverse problems… read more here.
Keywords: realistic acoustic; photoacoustic tomography; quantitative photoacoustic; acoustic media ... See more keywords
Direct and quantitative capture of viable bacteriophages from experimentally contaminated indoor air: A model for the study of airborne vertebrate viruses including SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.15262
Abstract: Abstract Aim The air indoors has profound health implications as it can expose us to pathogens, allergens and particulates either directly or via contaminated surfaces. There is, therefore, an upsurge in marketing of air decontamination… read more here.
Keywords: air; sars cov; indoor air; study airborne ... See more keywords
Electrochemical Behavior and Direct Quantitative Determination of Paclitaxel
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DOI: 10.3389/fchem.2022.834154
Abstract: The electrochemical behavior and direct quantitative determination of paclitaxel, a poorly soluble drug made into microemulsion, were researched by cyclic voltammetry in acetate buffer solutions (pH = 4.0) at a glassy carbon electrode. The results… read more here.
Keywords: direct quantitative; behavior direct; electrochemical behavior; determination ... See more keywords