Cu(OAc)2-catalyzed direct radical C2 arylation of quinoline N-oxide with arylamines
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.03.009
Abstract: Abstract A Cu(OAc) 2 -catalyzed synthesis of 2-arylquinoline N -oxides with easily available arylamines is described. The main features of this reaction are mild reaction conditions, high functional-group tolerance, excellent regioselectivity, and good to excellent… read more here.
Keywords: arylation quinoline; oac catalyzed; direct radical; catalyzed direct ... See more keywords
Direct radical sulfonylation at α-C(sp3)-H of THF with sodium sulfinates in aqueous medium
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.02.021
Abstract: Abstract A direct transition-metal-free, convenient and highly regioselective synthesis of 2-alkyl/aryl sulfonyl tetrahydrofurans (THFs) has been achieved from THF and sodium sulfinates using K2S2O8 as a mild oxidant. This one-pot simple protocol involves an efficient… read more here.
Keywords: sodium sulfinates; aqueous medium; direct radical; thf sodium ... See more keywords
Direct radical alkylation and acylation of 2H-indazoles using substituted Hantzsch esters as radical reservoirs
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00507j
Abstract: A platform approach for the direct synthesis of 3-substituted 2H-indazole derivatives has been developed using a Ag(I)/Na2S2O8 system. This regioselective alkylation/acylation protocol operates under mild conditions, tolerates a wide range of structural moieties and delivers… read more here.
Keywords: radical alkylation; acylation indazoles; alkylation acylation; direct radical ... See more keywords
The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9020177
Abstract: Urolithin A is a metabolite generated from ellagic acid and ellagitannins by the intestinal microbiota after consumption of fruits such as pomegranates or strawberries. The objective of this study was to determine the cytoprotective capacity… read more here.
Keywords: direct radical; neuro cells; stress; metabolite urolithin ... See more keywords