Nickel-Catalyzed Direct Substitution of Allylic Alcohols with Nitriles: A General Tool for the Construction of Acyclic C2-Tertiary or Quaternary Benzyl Nitriles.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00323
Abstract: A nickel-catalyzed direct reaction of allylic alcohols with benzyl nitrile derivatives has been developed. The method provides an efficient route for the synthesis of nitriles bearing an α-tertiary or quaternary carbon center in good to… read more here.
Keywords: direct substitution; nickel catalyzed; allylic alcohols; catalyzed direct ... See more keywords
N-Heterocyclic Carbene-Catalyzed Synthesis of Ynones via C–H Alkynylation of Aldehydes with Alkynyliodonium Salts—Evidence for Alkynyl Transfer via Direct Substitution at Acetylenic Carbon
Sign Up to like & getrecommendations! Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b04394
Abstract: Alkynylation of aldehydes with alkynyl(aryl)iodonium salts catalyzed by an N-heterocyclic carbene (NHC) has been developed. The application of the organocatalyst and the hypervalent iodine group transfer reagent allowed for metal-free C–H functionalization and C–C bond… read more here.
Keywords: direct substitution; alkynylation aldehydes; substitution acetylenic; alkynyl transfer ... See more keywords