Photoredox-Enabled Direct and Three-Component Difluoroalkylative Modification of N-Aryl Glycinates.
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DOI: 10.1021/acs.orglett.4c04826
Abstract: A Cu(I) photoredox-enabled reaction that selectively incorporates a difluoroalkyl group into N-aryl glycine derivatives has been established. Using a bench-stable [Ph3PCF2H]+Br- salt, the -CF2H group could be installed either directly on the α-carbon of the… read more here.
Keywords: component difluoroalkylative; photoredox enabled; direct three; three component ... See more keywords