Evaluation of intravenous direct thrombin inhibitor monitoring tests: Correlation with plasma concentrations and clinical outcomes in hospitalized patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-019-01961-3
Abstract: The parenterally administered direct thrombin inhibitors (DTIs) argatroban and bivalirudin are effective anticoagulants for acute heparin-induced thrombocytopenia (HIT) treatment. The activated partial thromboplastin time (aPTT) has classically been used as the monitoring test to assess… read more here.
Keywords: dtt; discordance; direct thrombin; monitoring ... See more keywords
SUBSEQUENT CHANGES IN DOSING REQUIREMENTS TO PRODUCE THERAPEUTIC ANTICOAGULATION WITH INJECTABLE DIRECT THROMBIN INHIBITORS AFTER INSTITUTIONAL CHANGE TO THE ACTIVATED PARTIAL THROMBOPLASTIN TIME REAGENT
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)32645-7
Abstract: Injectable direct thrombin inhibitors (iDTI) argatroban and bivalirudin are useful in the management of patients with documented or suspected heparin induced thrombocytopenia (HIT). Management of iDTIs includes monitoring with the activated partial thromboplastin time (aPTT)… read more here.
Keywords: thromboplastin time; direct thrombin; injectable direct; thrombin inhibitors ... See more keywords
Short‐term efficacy and safety of antithymocyte globulin treatment in elderly patients with acquired aplastic anaemia
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Haematology"
DOI: 10.1111/bjh.14372
Abstract: Blech, S., Ebner, T., Ludwig-Schwellinger, E., Stangier, J. & Roth, W. (2008) The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metabolism and Disposition, 36, 386–399. Glund, S., Stangier, J.,… read more here.
Keywords: term; safety; oral direct; efficacy ... See more keywords
Atrial Fibrillation in a Patient with Heparin-induced Thrombocytopenia Successfully Treated by Radiofrequency Catheter Ablation Using a Direct Thrombin Inhibitor
Sign Up to like & getrecommendations! Published in 2022 at "Internal Medicine"
DOI: 10.2169/internalmedicine.9288-21
Abstract: A 74-year-old man was admitted to our hospital to undergo radiofrequency catheter ablation (RFCA) of persistent atrial fibrillation (AF). We found that he had a history of heparin-induced thrombocytopenia (HIT). Thus, a direct thrombin inhibitor,… read more here.
Keywords: thrombin inhibitor; direct thrombin; radiofrequency catheter; catheter ablation ... See more keywords