Articles with "directed cell" as a keyword



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Self-Directed in Cell Production of Methionine Analogue Azidohomoalanine by Synthetic Metabolism and Its Incorporation into Model Proteins.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7574-7_7

Abstract: Common protocols for the incorporation of noncanonical amino acids (ncAAs) into proteins require addition of the desired ncAA to the growth medium, its cellular uptake, and subsequent intracellular accumulation. This feeding scheme is generally suitable… read more here.

Keywords: directed cell; azidohomoalanine; self directed; production methionine ... See more keywords
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Abstract 1877: Coordination of Rac1 and Cdc42 by centrosomal microtubules in focal adhesion dynamics and directed cell migration

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Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-1877

Abstract: Cancer metastasis causes the increase of mortality in most cancer patients, and abnormal cell migration contributes to this disease progression. To control cell migration, the dynamical control of a protein complex within focal adhesions has… read more here.

Keywords: directed cell; focal adhesion; cell migration; centrosomal microtubules ... See more keywords
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Microtubule detyrosination drives symmetry breaking to polarize cells for directed cell migration.

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Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.2139/ssrn.4156165

Abstract: To initiate directed movement, cells must become polarized, establishing a protrusive leading edge and a contractile trailing edge. This symmetry-breaking process involves reorganization of cytoskeleton and asymmetric distribution of regulatory molecules. However, what triggers and… read more here.

Keywords: cell; detyrosination; symmetry breaking; cell migration ... See more keywords
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Sphingomyelin Depletion Inhibits CXCR4 Dynamics and CXCL12-Mediated Directed Cell Migration in Human T Cells

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.925559

Abstract: Sphingolipids, ceramides and cholesterol are integral components of cellular membranes, and they also play important roles in signal transduction by regulating the dynamics of membrane receptors through their effects on membrane fluidity. Here, we combined… read more here.

Keywords: cell; cxcl12 mediated; sphingomyelin depletion; cell migration ... See more keywords
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In vivo Neural Crest Cell Migration Is Controlled by “Mixotaxis”

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Published in 2020 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2020.586432

Abstract: Directed cell migration is essential all along an individual’s life, from embryogenesis to tissue repair and cancer metastasis. Thus, due to its biomedical relevance, directed cell migration is currently under intense research. Directed cell migration… read more here.

Keywords: directed cell; cell migration; cell; neural crest ... See more keywords
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Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23147870

Abstract: Acute kidney injury (AKI) is a common complication of severe human diseases, resulting in increased morbidity and mortality as well as unfavorable long-term outcomes. Although the mammalian kidney is endowed with an amazing capacity to… read more here.

Keywords: cell; depletion; cell migration; injury ... See more keywords