Methyltransferase-directed covalent coupling of fluorophores to DNA† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc04229e Click here for additional data file.
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DOI: 10.1039/c6sc04229e
Abstract: Highly efficient DNA labelling using an enzymatically-directed, strain-promoted azide–alkyne cycloaddition. read more here.
Keywords: methyltransferase directed; directed covalent; fluorophores dna; covalent coupling ... See more keywords
Abstract 1162: The evaluation of INCB059872, an FAD-directed covalent inhibitor of LSD1, in preclinical models of Ewing sarcoma
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-1162
Abstract: Ewing sarcoma is a rare bone cancer affecting predominantly children. The chromosomal translocation of chromosomes 11 and 22 results in the EWS/FLI gene fusion oncoprotein that is associated with ~85% of Ewing sarcoma cases. The… read more here.
Keywords: fad directed; ews fli; incb059872; ewing sarcoma ... See more keywords