Discovery of a Biologically Active Bromodomain Inhibitor by Target-Directed Dynamic Combinatorial Chemistry.
Sign Up to like & getrecommendations! Published in 2018 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.8b00247
Abstract: Target-directed dynamic combinatorial chemistry (DCC) has emerged as a strategy for the identification of inhibitors of relevant therapeutic targets. In this contribution, we use this strategy for the identification of a high-affinity binder of a… read more here.
Keywords: dynamic combinatorial; target directed; combinatorial chemistry; chemistry ... See more keywords
Global Directed Dynamic Behaviors of a Lotka-Volterra Competition-Diffusion-Advection System
Sign Up to like & getrecommendations! Published in 2021 at "Axioms"
DOI: 10.3390/axioms10030195
Abstract: This paper investigates the problem of the global directed dynamic behaviors of a Lotka-Volterra competition-diffusion-advection system between two organisms in heterogeneous environments. The two organisms not only compete for different basic resources, but also the… read more here.
Keywords: system; diffusion; global directed; directed dynamic ... See more keywords