Dietary stigmastane-type saponins as promising dual-target directed inhibitors of SARS-CoV-2 proteases: a structure-based screening
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DOI: 10.1039/d1ra05976a
Abstract: Vernonia amygdalina derived phytochemicals as potential dual-target directed inhibitors of SARS-CoV-2 proteases from computational study perspective. read more here.
Keywords: dual target; target directed; inhibitors sars; cov proteases ... See more keywords
Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia
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DOI: 10.1186/s12943-018-0805-1
Abstract: The introduction of ABL Tyrosine Kinase Inhibitors (TKIs) has significantly improved the outcome of Chronic Myeloid Leukemia (CML) patients that, in large part, achieve satisfactory hematological, cytogenetic and molecular remissions. However, approximately 15–20% fail to… read more here.
Keywords: myeloid leukemia; non abl; chronic myeloid; leukemia ... See more keywords