Substrate-directed novel direct amidation of resin-bound amino acids
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DOI: 10.1093/chemle/upae107
Abstract: In peptide drug discovery, the C-terminal structure of peptide compounds is crucial for enhancing the affinity with target proteins and for optimizing the compound's dynamics and physical properties. In conventional solid-phase synthesis, two steps are… read more here.
Keywords: direct amidation; directed novel; novel direct; substrate directed ... See more keywords