Abstract 6493: CRISPR-directed prime editing sensitizes EGFR inhibitor by correcting oncogenic KRAS mutants In NSCLC
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DOI: 10.1158/1538-7445.am2024-6493
Abstract: EGFR inhibitor has been demonstrated with huge therapeutic potential in advanced non-small cell lung cancer (NSCLC), while the patients carrying KRAS mutation had poor response to EGFR inhibitor. KRAS mutation is the most frequent molecular… read more here.
Keywords: crispr directed; kras mutants; egfr inhibitor; directed prime ... See more keywords