SIRT1 directly activates autophagy in human chondrocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Cell death discovery"
DOI: 10.1038/s41420-020-0277-0
Abstract: Osteoarthritis (OA) is the most common form of arthritis worldwide with no effective treatment. Ageing is the primary risk factor for OA. We sought to investigate if there is a distinct and functional convergence of… read more here.
Keywords: activates autophagy; chondrocytes sirt1; directly activates; autophagy chondrocytes ... See more keywords
miR-1306-3p directly activates P2X3 receptors in primary sensory neurons to induce visceral pain in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Pain"
DOI: 10.1097/j.pain.0000000000002853
Abstract: ABSTRACT Mounting evidence indicates that microRNAs (miRNAs) play critical roles in various pathophysiological conditions and diseases, but the physiological roles of extracellular miRNAs on the disease-related ion channels remain largely unknown. Here, we showed that… read more here.
Keywords: 1306 directly; mir 1306; pain; directly activates ... See more keywords