Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids
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DOI: 10.1038/s41556-019-0445-8
Abstract: Defining the ontogeny of the human adaptive immune system during embryogenesis has implications for understanding childhood diseases including leukaemias and autoimmune conditions. Using RAG1:GFP human pluripotent stem cell reporter lines, we examined human T-cell genesis… read more here.
Keywords: rag1; directly haemogenic; stem cell; pluripotent stem ... See more keywords