Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia.
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DOI: 10.1158/2159-8290.cd-22-0366
Abstract: The dysregulation of developmental and stem cell associated genes is a common phenomenon during cancer development. Around half of acute myeloid leukemia (AML) patients express high levels of HOXA cluster genes and MEIS1. Most of… read more here.
Keywords: directly regulates; regulates oncogenic; acute myeloid; myeloid leukemia ... See more keywords