Kinetics of Reactions of Dirhodium and Diruthenium Paddlewheel Tetraacetate Complexes with Nucleophilic Protein Sites: Computational Insights.
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DOI: 10.1021/acs.inorgchem.2c02516
Abstract: Recently, dirhodium and diruthenium paddlewheel complexes have drawn attention as perspective anticancer drugs. In this study, the kinetics of reaction of typical paddlewheel scaffolds Rh2(μ-O2CCH3)4(H2O)2, Ru2(μ-O2CCH3)4(H2O)Cl, and [Ru2(μ-O2CCH3)4(HO)Cl]- with protein nucleophiles were investigated by means… read more here.
Keywords: substitution; diruthenium paddlewheel; paddlewheel; dirhodium diruthenium ... See more keywords