The Ubiquitin System: a Regulatory Hub for Intellectual Disability and Autism Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01881-x
Abstract: Intellectual disability (ID) and autism spectrum disorder (ASD) are two of the most common neurodevelopmental disorders. Both disorders are extremely heterogenous, and only ~ 40% of reported cases have so far been attributed to genetic mutations.… read more here.
Keywords: intellectual disability; disability autism; spectrum disorder; ubiquitin system ... See more keywords
Parental expectations for children with intellectual disability or autism in Ghana and Zambia: A concept mapping study.
Sign Up to like & getrecommendations! Published in 2021 at "Research in developmental disabilities"
DOI: 10.1016/j.ridd.2021.103989
Abstract: INTRODUCTION Parent expectations have an important impact on children's outcomes. Despite a wealth of research on the familial experience of children with disabilities in African countries, very few studies have examined expectations these children's parents… read more here.
Keywords: intellectual disability; disability autism; expectations children; children intellectual ... See more keywords
Understanding intellectual disability and autism spectrum disorders from common mouse models: synapses to behaviour
Sign Up to like & getrecommendations! Published in 2019 at "Open Biology"
DOI: 10.1098/rsob.180265
Abstract: Normal brain development is highly dependent on the timely coordinated actions of genetic and environmental processes, and an aberration can lead to neurodevelopmental disorders (NDDs). Intellectual disability (ID) and autism spectrum disorders (ASDs) are a… read more here.
Keywords: mouse models; spectrum disorders; intellectual disability; disability autism ... See more keywords
Stopping over-medication of people with an intellectual disability, autism or both (STOMP) in England part 2 – the story so far
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Mental Health and Intellectual Disabilities"
DOI: 10.1108/amhid-02-2018-0005
Abstract: Purpose The STOMP programme – stopping the over-medication of people with an intellectual disability, autism or both is a three-year programme supported by NHS England. Concern about the overuse of antipsychotic drugs has been a… read more here.
Keywords: intellectual disability; methodology; medication; people intellectual ... See more keywords
A case to ruminate on: vomiting and weight loss in intellectual disability and autism
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Mental Health and Intellectual Disabilities"
DOI: 10.1108/amhid-12-2018-0054
Abstract: Purpose The purpose of this paper is to review a case of a man with intellectual disability, autism and challenging behaviour who presented with vomiting, regurgitations and significant weight loss. Design/methodology/approach The paper examines the… read more here.
Keywords: intellectual disability; weight loss; disability autism; case ... See more keywords
Dental procedures in children with or without intellectual disability and autism spectrum disorder in a hospital setting.
Sign Up to like & getrecommendations! Published in 2022 at "Australian dental journal"
DOI: 10.1111/adj.12927
Abstract: BACKGROUND This population-based cohort study investigated dental procedures in the hospital setting in Western Australian children with or without intellectual disability and/or autism spectrum disorder aged up to 18 years. Considering previously reported disparities in dental… read more here.
Keywords: intellectual disability; disability; autism spectrum; disability autism ... See more keywords
Acknowledging caregivers’ vulnerability in the managment of challenging behaviours to reduce control measures in psychiatry
Sign Up to like & getrecommendations! Published in 2022 at "Nursing Ethics"
DOI: 10.1177/09697330211015275
Abstract: Background: The management of challenging behaviours in inpatient with intellectual disability and/or autism spectrum disorders can lead to an escalation of control measures. In these complex situations where patients have an intellectual disability/autism spectrum disorder… read more here.
Keywords: vulnerability; intellectual disability; challenging behaviours; control ... See more keywords
Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1006864
Abstract: Kleefstra syndrome, caused by haploinsufficiency of euchromatin histone methyltransferase 1 (EHMT1), is characterized by intellectual disability (ID), autism spectrum disorder (ASD), characteristic facial dysmorphisms, and other variable clinical features. In addition to EHMT1 mutations, de… read more here.
Keywords: intellectual disability; autism spectrum; disability autism; spectrum ... See more keywords
Adults with Intellectual Disability and Autism Spectrum Disorder: What Is the Evidence around the Use of Polypharmacy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192315974
Abstract: A review on the mental health needs of adults with intellectual disability (ID) and autism spectrum disorder (ASD) published just over 10 years ago found a limited evidence base for pharmacological intervention in this group.… read more here.
Keywords: intellectual disability; polypharmacy; adults intellectual; disability autism ... See more keywords