Increased Disability Progression in rs10191329AA Carriers with Multiple Sclerosis Is Preceded by Neurofilament Light Chain Elevations
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DOI: 10.1002/ana.27144
Abstract: We examined the impact of the rs10191329 genetic risk variant on neuroaxonal damage as measured by serum neurofilament light chain (sNfL) levels, and disability progression in people with multiple sclerosis (pwMS). read more here.
Keywords: disability progression; neurofilament light; light chain; multiple sclerosis ... See more keywords
Diffusion tensor imaging and disability progression in multiple sclerosis: A 4‐year follow‐up study
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DOI: 10.1002/brb3.1194
Abstract: Diffusion tensor imaging (DTI) is sensitive technique to detect widespread changes in water diffusivity in the normal‐appearing white matter (NAWM) that appears unaffected in conventional magnetic resonance imaging. We aimed to investigate the prognostic value… read more here.
Keywords: multiple sclerosis; tensor imaging; diffusion tensor; disability progression ... See more keywords
Early-life and adult body mass index in relation to MS disability progression
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DOI: 10.1007/s00415-025-13319-2
Abstract: The influence of body weight across the life course on multiple sclerosis (MS) progression remains incompletely understood. While excess body mass at diagnosis is associated with disability progression, it is unclear how early-life and adult… read more here.
Keywords: diagnosis; disability progression; progression; bmi ... See more keywords
Long-term disease activity and disability progression in relapsing-remitting multiple sclerosis patients on natalizumab.
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DOI: 10.1016/j.msard.2019.05.017
Abstract: BACKGROUND Natalizumab is an effective treatment for relapsing-remitting multiple sclerosis (RRMS). Data on clinical and imaging measures predictive of disease activity and progression during treatment is limited. OBJECTIVE To determine clinical and imaging predictors of… read more here.
Keywords: disability progression; disease; disease activity; multiple sclerosis ... See more keywords
CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis
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DOI: 10.1038/s41467-024-49312-y
Abstract: Multiple sclerosis (MS) is characterized by heterogeneity in disease course and prediction of long-term outcome remains a major challenge. Here, we investigate five myeloid markers – CHIT1, CHI3L1, sTREM2, GPNMB and CCL18 – in the… read more here.
Keywords: disability progression; faster disability; multiple sclerosis; disability ... See more keywords
The Non-motor Symptoms, Disability Progression, and Survival Analysis of Atypical Parkinsonism: Case Series from Eastern India and Brief Review of Literature
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DOI: 10.1055/s-0042-1744120
Abstract: Objective The objectives of this study are (1) to describe the non-motor profile, the motor disability progression, and survival analysis of atypical parkinsonism in a tertiary care hospital of eastern India and (2) to elucidate… read more here.
Keywords: msa; disability progression; motor; non motor ... See more keywords
Smoking and disability progression in multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2020 at "Expert review of neurotherapeutics"
DOI: 10.1080/14737175.2020.1743176
Abstract: ISSN: 1473-7175 (Print) 1744-8360 (Online) Journal homepage: https://www.tandfonline.com/loi/iern20 Smoking and disability progression in multiple sclerosis Anna Karin Hedström To cite this article: Anna Karin Hedström (2020): Smoking and disability progression in multiple sclerosis, Expert Review… read more here.
Keywords: multiple sclerosis; progression multiple; smoking disability; disability progression ... See more keywords
Projections of dependency and associated social care expenditure for the older population in England to 2038: effect of varying disability progression
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DOI: 10.1093/ageing/afac158
Abstract: Abstract Objectives to assess the effect of recent stalling of life expectancy and various scenarios for disability progression on projections of social care expenditure between 2018 and 2038, and the likelihood of reaching the Ageing… read more here.
Keywords: disability progression; care; care expenditure;
Later-Life Disability in Environmental Context: Why Living Arrangements Matter
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DOI: 10.1093/geront/gnx019
Abstract: Background and Objectives Household social and environmental context are key elements of the disablement process, yet few studies explicitly examine the relationship between household composition, housing type, and disability progression. This study investigates the risk… read more here.
Keywords: household; disability; disability progression; living arrangements ... See more keywords
Disability progression in multiple sclerosis patients using early first‐line treatments
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DOI: 10.1111/ene.15422
Abstract: Therapeutic management of relapsing–remitting multiple sclerosis (RRMS) has evolved towards early treatment. The objective was to assess the impact of early treatment initiation on disability progression amongst RRMS first‐line‐treated patients. read more here.
Keywords: disability progression; multiple sclerosis; first line;
Association of Choroid Plexus Inflammation on MRI With Clinical Disability Progression Over 5 Years in Patients With Multiple Sclerosis
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DOI: 10.1212/wnl.0000000000201608
Abstract: Background and Objectives Inflammation of the choroid plexus (CP) has been reported in multiple sclerosis (MS). The AU1 association between CP inflammation and clinical disability progression is still under debate. The objective of the current… read more here.
Keywords: inflammation; progression; volume; disability progression ... See more keywords