Chemical disaggregation of alpha-synuclein fibrils as a therapy for synucleinopathies.
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DOI: 10.1073/pnas.2300965120
Abstract: Protein aggregate formed by alpha-synuclein is the hallmark of a series of neurodegenerative disorders known as synucleinopathies (also known as Lewy body diseases), including Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy… read more here.
Keywords: synuclein; alpha synuclein; synuclein fibrils; disaggregation alpha ... See more keywords