Association Between Switching to a High-Deductible Health Plan and Discontinuation of Type 2 Diabetes Treatment.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2019.14372
Abstract: Importance High-deductible health plans (HDHPs) are a common cost-savings option for employers but may lead to underuse of necessary treatments because beneficiaries bear the full cost of health care, including medications, until a deductible is… read more here.
Keywords: non hdhp; association; cohort; discontinuation ... See more keywords
Evaluation of Inequities in Cancer Treatment Delay or Discontinuation Following SARS-CoV-2 Infection
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.51165
Abstract: Key Points Question Among individuals with cancer, are members of racial and ethnic minority groups and those residing in socioeconomically disadvantaged areas more likely to experience cancer treatment delays and discontinuation after SARS-CoV-2 infection relative… read more here.
Keywords: cov infection; discontinuation; treatment; cancer treatment ... See more keywords
Comparative Effectiveness of Rituximab and Other Initial Treatment Choices for Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.4011
Abstract: Importance Comparative real-world effectiveness studies of initial disease-modifying treatment (DMT) choices for relapsing-remitting multiple sclerosis (RRMS) that include rituximab are lacking. Objective To assess the effectiveness and drug discontinuation rates of rituximab among patients with… read more here.
Keywords: dmts; initial treatment; treatment; discontinuation ... See more keywords
Timing of Antidepressant Discontinuation During Pregnancy and Postpartum Psychiatric Outcomes in Denmark and Norway
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2023.0041
Abstract: Key Points Question Are longitudinal antidepressant fill trajectories during pregnancy associated with postpartum psychiatric outcomes? Findings In this cohort study of 57 934 pregnancies and 4 antidepressant fill trajectory groups in Denmark and Norway, early discontinuation… read more here.
Keywords: psychiatric outcomes; postpartum psychiatric; pregnancy; discontinuation ... See more keywords
Medication Use for Obesity-Related Comorbidities After Sleeve Gastrectomy or Gastric Bypass.
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DOI: 10.1001/jamasurg.2021.6898
Abstract: Importance Sleeve gastrectomy and gastric bypass are the most common bariatric surgical procedures in the world; however, their long-term medication discontinuation and comorbidity resolution remain unclear. Objective To compare the incidence of medication discontinuation and… read more here.
Keywords: discontinuation; sleeve gastrectomy; medication; gastric bypass ... See more keywords
The impact of COVID‐19 on autism research: A cross‐sectional analysis of discontinued or suspended clinical trials
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DOI: 10.1002/aur.2764
Abstract: Due to uncertainties associated with the COVID‐19 public health crisis, several clinical trials had to be withdrawn or postponed. Our investigation aimed to assess the rate of discontinuation of clinical trials focusing on Autism Spectrum… read more here.
Keywords: impact covid; clinical trials; autism; autism research ... See more keywords
SLCO1B1*5 Allele Is Associated With Atorvastatin Discontinuation and Adverse Muscle Symptoms in the Context of Routine Care
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DOI: 10.1002/cpt.2527
Abstract: The SLCO1B1 genotype is known to influence patient adherence to statin therapy, in part by increasing the risk for statin‐associated musculoskeletal symptoms (SAMSs). The SLCO1B1*5 allele has previously been associated with simvastatin discontinuation and SAMSs.… read more here.
Keywords: atorvastatin discontinuation; muscle; routine care; discontinuation ... See more keywords
Frequency of and factors associated with antiseizure medication discontinuation discussions and decisions in patients with epilepsy: A multicenter retrospective chart review
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DOI: 10.1002/epi4.12695
Abstract: Guidelines suggest considering antiseizure medication (ASM) discontinuation in patients with epilepsy who become seizure‐free. Little is known about how discontinuation decisions are being made in practice. We measured the frequency of, and factors associated with,… read more here.
Keywords: patients epilepsy; antiseizure medication; discussions decisions; frequency factors ... See more keywords
Clinical value of routine [18F]2‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography scans as a decision tool for early immunotherapy discontinuation in advanced melanoma
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DOI: 10.1002/ijc.33926
Abstract: Routine [18F]2‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography (FDG‐PET) may help predict clinical outcomes after response to immunotherapy. With a European Medicines Agency‐recommended treatment length until disease progression or unacceptable toxicity, the optimal duration of immunotherapy remains to… read more here.
Keywords: 18f fluoro; immunotherapy; routine 18f; fluoro deoxy ... See more keywords
Distinct Responses of Modeling‐ and Remodeling‐Based Bone Formation to the Discontinuation of Intermittent Parathyroid Hormone Treatment in Ovariectomized Rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4704
Abstract: Anabolic agents, such as intermittent parathyroid hormone (PTH), exert their treatment efficacy through activation of two distinct bone formation processes, namely, remodeling‐based bone formation (RBF, bone formation coupled with prior bone resorption) and modeling‐based bone… read more here.
Keywords: bone formation; bone; discontinuation; treatment ... See more keywords
Defecatory dysfunction and other clinical variables are predictors of pessary discontinuation
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DOI: 10.1007/s00192-018-3777-1
Abstract: Introduction and hypothesisPessaries provide first-line therapy for women with pelvic organ prolapse (POP) and stress urinary incontinence (SUI). The primary hypothesis was that defecatory dysfunction was associated with pessary discontinuation.MethodsThis was a retrospective cohort study… read more here.
Keywords: associated pessary; pessary discontinuation; defecatory dysfunction; discontinuation ... See more keywords